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pentobarbital will lower the level or influence of capivasertib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Solid or average CYP3A inducers minimize capivasertib exposure, which can decrease efficacy.pentobarbital will lower the extent or impact of elbasvir/grazoprevir by influencing hepatic/intestinal enz